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It circulates at relatively high concentrations when you're young, around 200 ng/mL in your 20s , and drops steadily with age, reaching roughly 80 ng/mL by your 60s

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Physicians report major concerns about patient education, unrealistic expectations, rising healthcare costs, supply issues for diabetes patients, and widening health inequities

One challenge to elucidating a mechanistic role for GLP-1Rs stems from their complex expression across multiple brain regions (1012), including the lateral septal nucleus (LSc), substantia nigra, ventral tegmental area (VTA), amygdala, nucleus accumbens (ACB), hippocampus, several regions of the hypothalamus (paraventricular nucleus of the hypothalamus [PVH], arcuate nucleus [ARH]), and hindbrain